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ManuCyte

Full name: Self-learning modular manufacturing platform for flexible, patient specific cell production
Homepage: http://www.manucyte-project.eu/
Department: Computer Integrated Manufacturing Laboratory
Start date: 2010. 05. 01.
End date: 2013. 04. 31.
External identifier: FP7 260100
Cost: 3.435.700 euro

Project manager

János Nacsa

Address: 1111 Budapest, Kende u. 13-17.
Room number: K 421
Phone: +36 1 279 6268
Fax: +36 1 4667503
E-mail: nacsa.janosEZT_TOROLJE_KI@EZT_TOROLJE_KIsztaki.mta.hu

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Members

Sándor Kopácsi

Address: 1111 Budapest, Kende u. 13-17.
Room number: K 421
Phone: +36 1 279 6268
Fax: +36 1 466 7503
E-mail: kopacsi.sandorEZT_TOROLJE_KI@EZT_TOROLJE_KIsztaki.mta.hu

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György Kovács

Address: 1111 Budapest, Kende u. 13-17.
Room number: K 424
Phone: +36 1 279 6140
Fax: +36 1 4667503
E-mail: kovacs.gyorgyEZT_TOROLJE_KI@EZT_TOROLJE_KIsztaki.mta.hu

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Géza Haidegger

Address: 1111 Budapest, Kende u. 13-17.
Room number: K 423
Phone: +36 1 279 6207, +36 1 279 6224
Fax: +36 1 4667503
E-mail: haidegger.gezaEZT_TOROLJE_KI@EZT_TOROLJE_KIsztaki.mta.hu
Homepage: http://www.sztaki.hu/munkatars/008001106/

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Participants

Description

ManuCyte focuses on the development of an intelligent, modular manufacturing platform for flexible, patient-specific cell production which will increase efficiency of personalised cell production in terms of quality, throughput, and costs. This objective will be reached by combining several high-sophisticated technologies such as
- a modular and scalable concept for the setup of cell production platforms, which is based on plug-ins and allows a flexible composition of functionalities, extension of capacities, as well as fast ramp up.
- a micro-fluidic component which provides cell culture medium specifically customised for each cell culture.
- bioreactors with integrated sensor technology, which are capable for highly automated processes as well as the associated incubation component
- the application of a cost-neutral cleanroom and sterilisation concept to keep cell cultures free of contaminations from the environment and between different cell cultures.
- optical and biochemical inline monitoring methodologies, which enable the evaluation of cell status within the production process
- a MES (Manufacturing Execution System) with LIMS (Laboratory Information and Management System) functionalities
- a self-learning knowledge-based cell behaviour model and advanced cell process control functionalities.